Apr - Phil Bourne¶
Speaker: Phil Bourne
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Talk Title: What Really Happens When We Take a Drug?
Thursday, April 12th, 2011, 6:00 pm
Affiliation: Professor, Department of Pharmacology and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego
Associate Director, RCSB Protein Data Bank and Adjunct Professor, Burnham Institute
URL: Philip E. Bourne
This is a question which, after generic clinical trials, is still very much answered by observing patient outcomes. Methods from bioinformatics and systems biology are making some inroads into answering this question more systematically through integration of a variety of data sources and important algorithmic developments. I will dig in to some of our work in this area, but if you cant wait refer to Xie et al. (2012) Annual Review of Pharmacology and Toxicology 52: 361-379. I’ll also describe the importance of open science to this collective effort.
Trainees are invited to meet with the VanBUG speaker for open discussion of both science and career paths. This takes place 4:30-5:30pm in either the Boardroom or Lunchroom on the ground floor of the BCCRC
Introductory Speaker: Andrew McPherson, PhD candidate, Sahinalp lab, SFU and Huntsman lab, UBC
Title: Predicting the complex origins of chimeric transcripts using nFuse