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Vancouver Bioinformatics Users Group

VanBUG (Vancouver Bioinformatics Users Group) is an association of researchers, other professionals and students in the B.C. Lower Mainland who have an interest in the field of bioinformatics.

VanBUG meets on the second Thursday of every month from September through April. Research presentations by bioinformatics leaders, students and industry representatives are followed by networking over pizza and refreshments

Meetings are held in the Gordon and Leslie Diamond Family Theatre, BC Cancer Research Centre, 675 West 10th Avenue at 6:00 pm and are free and open to all.

As a service to the community, other bioinformatics events are posted to the Calendar
Visit our sister groups for bioinformatics events in Montreal (MonBUG) and now Toronto (TorBUG)!

next speakers:

Melissa Wilson Sayres

Talk Title:
“Sex-biased genome evolution”

Thursday, May 11, 2017 6:00pm

Assistant Professor, School of Life Sciences and the Center for Evolution and Medicine, The Biodesign Institute, Arizona State University.

Web-site: Melissa Wilson Sayres
Twitter: @mwilsonsayres

The human X and Y chromosomes evolved from a pair of homologous autosomes, but today have vastly different gene content and structure. Curiously, despite tremendous sex-bias in human disease, the sex chromosomes are rarely included in genome-wide analyses of human health and disease. One of the reasons for this exclusion is that the X and Y chromosomes don’t follow autosomal patterns of inheritance. However, even when they are included, technical biases resulting from aligning all sequences to a single reference genome can result in erroneous results. I will present results that failing to account for the ancestral sequence similarity between the human X and Y can affect variant calling and inference of gene expression.

Dr. Melissa Wilson Sayres is an Assistant Professor in the School of Life Sciences and the Center for Evolution and Medicine at Arizona State University. Her main research interests are in sex-biased genetics, mutational processes, and population dynamics. In particular she is studying how the human X and Y chromosome came to be, and what this means for human health and disease. She has trained more than 40 students in how to do scientific research. In addition to her research, she is an enthusiastic educator, teaching about 400 students each year at Arizona State University, most notably in Evolution.

Please note:
Trainees are invited to meet with the VanBUG speaker for open discussion of both science and career paths. This takes place 5:00-5:45pm in either the Boardroom or Lunchroom on the ground floor of the BCCRC

Recommended Readings


Introductory Speaker:
Melissa Chen (Master’s student, Laura Parfrey’s lab, UBC)

“Quantification of Species Turnover along Salinity Gradients”


Webcast Link:
(This technology is brought to you by Compute Canada and WestGrid with support from PHSA Telehealth)

To view previous VanBUG posters and presentations, please see Archives

sponsored by:

CIHR Bioinformatics Training Program

Canadian Bioinformatics Workshops

Genome BC

Proof Centre

past sponsors:


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