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 Ryan Brinkman

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Talk Title:
An Open Source Software Framework for High-Throughput Flow Cytometry Data Analysis and its Application to Discovery and Diagnosis

Date/Time:
September 10, 2009, 6:00pm

Affiliation:
Terry Fox Laboratories, BC Cancer Research Centre

URL:
Ryan Brinkman

Abstract:
High-throughput FCM (HT-FCM) is poised to reshape dramatically biomedical research by increasing the efficiency of an already widely adopted research and clinical tool. However, accelerating data collection requires a similar increase in the ability to analyze data. Successful management of the information generated by HT-FCM techniques requires highly automated methods to extract the relevant information from the large volume of data generated by the measurement of complex treatment-response patterns. This talk will review the development of an integrated computational infrastructure supporting high throughput data quality analysis, normalization, automated gating and sophisticated visualization. Examples will be shown illustrating how we have applied the various tools to support both the discovery of clinical relevant cell populations and aid in patient diagnosis.

Presentation:
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Introductory Speaker:
Andrew McPherson, Bioinformatics Graduate Program

Talk Title:
Methods for gene fusion discovery using RNA-seq

Affiliation:
Centre for Translational and Applied Genomics (CTAG), BC Cancer Research Centre

The upcoming 2009-2010 meeting dates

September 10, 2009
October 8, 2009
November 12, 2009
December 10, 2009
January 14, 2010
March 11, 2010
April 8, 2010