William NobleCo-sponsored with
Talk Title:
Computational Analyses of Yeast and Human Chromatin
Date/Time:
October 9, 2008, 6:00pm
Affiliation:
University of Washington, Department of Genome Sciences
URL:
William Noble
Abstract:
In the nucleus of the eukaryotic cell, DNA is wrapped into a complex,
dynamic molecular structure known as chromatin. Over the past
several years, we have collaborated with experimental labs to create
and validate a series of computational models of chromatin in human
and yeast. In this talk, I will describe three models, which (1) predict
local chromatin organization from sequence, (2) delineate larger-scale
chromatin domains from high-throughput cleavage data, and (3)
identify protein-binding footprints on a genomewide scale.
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Introductory Speaker:
James Taylor
Talk Title:
High-Throughput Microfluidic Technologies for Systems Studies of Cellular Signaling
Affiliation:
Michael Smith Laboratories
Institute for Systems Biology
